Our specialised electrophysiology services in intact systems provide direct evidence of drug efficacy and mechanisms of action. Recordings can be performed in a range of states, including neuropathic, inflammatory and obesity models. Responses can be compared to in-house reference data generated using 'gold standard' compounds (e.g. gabapentin and morphine). Compound effects on mechanically, electrically and/or chemically evoked responses can all be studied utilising a range of electrophysiological techniques.

Specialised electrophysiology at NeuroSolutions Ltd. includes:

Central

• Single/multi-unit and field potential recordings
• Recordings from all characterised brain regions and nuclei
• Recordings from the spinal cord (e.g. dorsal horn neurons) and dorsal roots

Peripheral

• Recordings from peripheral nerve (whole nerve/single fibres)
• Recordings from peripheral ganglia (single/multi-unit)
• Recordings from whole organs/muscle groups as ECG/EMG/EEG